OI Studies on the organ known as your skin:




Below is an evidence-based inventory of 2025 Osteogenesis Imperfecta (OI) research outputs that explicitly mention swallowing, feeding, eating, chewing (mastication), or feeding support and were published or first publicly presented in 2025. I grouped outputs by type (peer-reviewed vs. conference presentation) and, where possible, I list the first-public date (e.g., ePub date or conference abstract-book release).


Peer-reviewed journal articles (published in 2025)


1. Gastrointestinal complaints in patients with osteogenesis imperfecta: The bright side of a rare genetic disorder
  •         Type: Full-length observational study
  •         Eating/swallowing relevance: Uses GI symptom domains that include “disrupted swallowing” (patient-reported outcomes) in assessing GI symptom burden            in OI.
  •        First public release: Epub 2025-07-09 (journal issue dated 2025 Nov).
2. Most infants with prenatal osteogenesis imperfecta diagnosis and poor prognosis survive: experience of a quaternary care osteogenesis imperfecta center

  •         Type: Clinical outcomes study (neonatal cohort)

  •         Eating/swallowing relevance: Reports feeding difficulty and need for feeding support a t discharge for infants with moderate–severe OI.

  •         Publication: 2025 (JBMR Plus).

3. Case Report: Holistic approach to management of an infant with severe osteogenesis imperfecta in the neonatal intensive care unit
             Type: Case report / care model discussion (NICU)
             Eati ng/swallowing relevance: Describes ongoing support needs including feeding/gastrostomy tubes in severe neonatal OI management.
             Publication: 2025 (Frontiers in Pediatrics).   


  1. Determinants of masticatory ability in Taiwanese patients with osteogenesis imperfecta

  •           Type: Dental/functional outcomes study

  •           Eating/swallowing relevance: Directly studies chewing (mastication) ability and factors predicting masticatory difficulty in OI.

  •           Publication: 2025 Apr (J Dent Sci)   


  1. Mastication and electrical activation in the masseter and anterior temporalis muscles of children and adolescents with osteogenesis imperfecta

  •           Type: Functional physiology / surface EMG study

  •           Eating/swallowing relevance: Chewing task analyses explicitly reference the interval “between the first incision and the last swallow,” linking mastication                   tasks to swallowing endpoints.

  •            Publication: 2025 (open-access via PMC).   


  1. Basilar invagination in osteogenesis imperfecta – Case report

  •           Type: Radiology case report

  •            Eating/swallowing relevance: While this report is primarily neuro/radiologic, basilar invagination in OI is clinically relevant because craniovertebral junction              pathology can present with bulbar symptoms (including swallowing impairment in general clinical contexts). This specific PubMed record documents the                2025 case report details.

  •             Publication: 2025 (Radiology Case Reports).
                            Note: The PubMed abstract text visible in the record is focused on neurological deficits; if you only want outputs that explicitly state                                                                  dysphagia/swallowing impairment in the abstract/full text, this item may need full-text confirmation beyond the PubMed abstract page.


  1. Early life functional transitions impact craniofacial morphology in osteogenesis imperfecta

  •           Type: Preclinical (mouse) craniofacial development study

  •            Eating/swallowing relevance: Explicitly frames development around the transition from suckling to mastication (feeding/chewing function) and how OI                     alters craniofacial growth.

  •            Publication: 2025 (open-access via PMC).   


Conference abstracts / posters first publicly presented in 2025


  1. DDW ePoster: “OSTEOGENESIS IMPERFECTA PATIENTS REPORT GASTROINTESTINAL COMPLAINTS…” (Tu1121)

  •            Type: Conference poster (Digestive Disease Week)

  •            Eating/swallowing relevance: The DDW ePoster listing indicates PROMIS GI symptom coverage including “disrupted swallowing.”

  •            First public presentation: Listed as part of DDW ePoster materials (the ePoster page snippet shows “May 6, 2025” in the search result listing).
                            Access note: The DDW ePoster page itself did not render content in my viewer (likely site restrictions), so the best available citation is the indexed                              ePoster listing snippet.


  1. ICOI 2025 (International Conference on Osteogenesis Imperfecta) – Abstract Book (Poster Presentations PDF): Neonatal survivors case series with feeding support details

  •            Type: Conference abstract (poster abstract in conference abstract book)

  •            Eating/swallowing relevance: Explicitly reports gastrostomy tube placement, nasogastric feeding, and oral feeding status at discharge/follow-up.

  •             First public presentation: Included in the ICOI 2025 poster abstract book (published online in 2025).


  1. ICOI 2025 – e-programme (conference programme PDF)

  •            Type: Conference programme artifact (context for what was presented in 2025)

  •             Eating/swallowing relevance: Not itself a swallowing/eating study, but it is a primary conference publication establishing the 2025 event framework and                  outputs pipeline. If you want a strict “only items that themselves mention swallowing/eating,” you can exclude this.

  •             First public release: Posted in 2025.