R-2026 -2 - Article published in 2026 on the ScienceAlert website, relating to a study first published in 2025, so it kind of falls between the two
Our mission is to provide comprehensive resources and support for those affected by Osteogenesis Imperfecta. By increasing awareness and building a supportive network, we aim to improve the quality of life for patients, caregivers, and healthcare professionals involved in the OI community.
Our team comprises dedicated individuals from diverse backgrounds, including healthcare professionals and community advocates. They share a unified commitment to enhancing the understanding and support for Osteogenesis Imperfecta, working tirelessly to connect and empower individuals within this community.
Health-related quality of life and fatigue in patients with osteogenesis imperfecta
Healthcare 14(12):1620 · PubMed 42354479
Quality of life & painCross-sectionalIn window
2026
Teriparatide plus zoledronic acid for osteogenesis imperfecta: a randomized clinical trial
JAMA · doi 10.1001/jama.2026.6889
Treatment trialsRCTVerify date
2026
Romosozumab in postmenopausal women with classical osteogenesis imperfecta
PMC13380549
Treatment trialsClinical studyVerify date
2026
Pediatric safety follow-up study of prior romosozumab treatment for OI
ClinicalTrials.gov NCT07366086
Treatment trialsTrial registrationVerify date
2026
Management of OI complicated by severe pneumonia in a resource-limited setting: a case report
PMC13054230
Cardiac & pulmonaryCase reportVerify date
2026
Progressive conductive hearing loss in OI (Lobstein disease): a case report
PMC13162037
Hearing & dentalCase reportVerify date
2026
Genetic analysis, reproductive decision-making and pregnancy outcomes in 51 Chinese OI families
J Assist Reprod Genet
Pregnancy & reproductionCohortVerify date
2026
The natural history of osteogenesis imperfecta: a systematic review
Bone Reports · PMC13266223
Natural history & epidemiologySystematic reviewVerify date
2026
OI: a registry-based study of the clinical symptoms of disease in a large cohort of Italian patients
Frontiers in Endocrinology
Natural history & epidemiologyRegistryVerify date
2026
A new perspective on OI: from cellular mechanisms to the systemic impact of collagen dysfunction
PMC12841275
Reviews & overviewsReviewVerify date
2026
What's new in osteogenesis imperfecta
PMC13092026
Reviews & overviewsReviewVerify date
2026
Osteogenesis imperfecta: it's more than the bones
PubMed 42419845
Reviews & overviewsReviewVerify date
Dec 29, 2025
Phase 3 Orbit and Cosmic results for setrusumab (UX143) in OI
Ultragenyx / Mereo BioPharma press release
Treatment trialsTrial readoutIn window
Sep 2025
Initial results of the TOPaZ study (ASBMR 2025 abstract)
ASBMR 2025 Annual Meeting
Treatment trialsConference abstractIn window
May 2025
Diagnosis of subclinical obstructive airways disease in OI through impulse oscillometry
Am J Respir Crit Care Med 211 Suppl A6884
Cardiac & pulmonaryConference abstractIn window
Feb 2025
J Bone Miner Res 40(2):211 · PubMed 39665364
Cardiac & pulmonaryConsensusIn window
2025
PubMed 41206390
Treatment trialsTrial reportIn window
2025
Romosozumab treatment in osteogenesis imperfecta type I
Journal of Bone Fragility 5(1)
Treatment trialsClinical studyIn window
2025
Denosumab in patients with OI and a historical control study with alendronate
PMC12148890
Bisphosphonates & denosumabClinical studyIn window
2025
Urinary calcium and bone resorption markers during 3 years of denosumab treatment in pediatric OI
JBMR Plus 9(10) · PubMed 40978125
Bisphosphonates & denosumabClinical studyIn window
2025
Archives of Osteoporosis
Bisphosphonates & denosumabMeta-analysisIn window
2025
Serum osteocalcin in pediatric OI: impact of disease type and bisphosphonate therapy
PubMed 40869278
Bisphosphonates & denosumabClinical studyIn window
2025
Conference abstract · PMC11771429
Bisphosphonates & denosumabCase / abstractIn window
2025
Cardiac manifestations in children with OI: a single-center observational study
International Journal of Cardiology
Cardiac & pulmonaryCohortIn window
2025
Minimally invasive aortic valve replacement in OI: a case report
PMC12504020
Cardiac & pulmonaryCase reportIn window
2025
Osteogenesis imperfecta as a cause of respiratory failure
QJM 118(4):279
Cardiac & pulmonaryClinical image / caseIn window
2025
Hearing loss in Chinese osteogenesis imperfecta patients
Eur Arch Otorhinolaryngol · PubMed 40220187
Hearing & dentalCohortIn window
2025
Perceived oral care needs and concerns of individuals with OI
PubMed 40335649
Hearing & dentalSurveyIn window
2025
PubMed 40570444
Hearing & dentalAnimal studyIn window
2025
Pregnancy-related complications in osteogenesis imperfecta
Obstetrics & Gynecology · PubMed 40472374
Pregnancy & reproductionCohortIn window
2025
Pregnancy with osteogenesis imperfecta: a scoping review
F1000Research 14:753
Pregnancy & reproductionScoping reviewIn window
2025
Health-related quality of life in individuals with OI in the United States: a cross-sectional study
PubMed 41131612
Quality of life & painCross-sectionalIn window
2025
JBMR Plus 9(7) ziaf076
Quality of life & painCross-sectionalIn window
2025
Mortality and fracture risk in children with OI: French nationwide hospital discharge database
Bone
Natural history & epidemiologyRegistryIn window
2025
Bone changes during growth in patients with osteogenesis imperfecta
PMC11900570
Natural history & epidemiologyCohortIn window
2025
Osteogenesis imperfecta or non-accidental trauma? The diagnostic dilemma in pediatric fractures
PubMed 41635462
Fractures vs. abuseQI case seriesIn window
2025
Commentary on quality improvement case series: “Osteogenesis imperfecta or non-accidental trauma”
PMC12595142
Fractures vs. abuseCommentaryIn window
2025
Pediatric bone fractures: challenges in differential diagnosis between child abuse and OI
PubMed 40728335
Fractures vs. abuseReviewIn window
2025
Clinical Genetics · PubMed 40650436
Genetics & basic scienceCohortIn window
2025
J Bone Miner Res 40(5):577
Genetics & basic scienceAnimal studyIn window
2025
New lens on congenital mild bone fragility: a novel Col1a1 knockout mouse model for OI type 1
J Bone Miner Res · doi 10.1093/jbmr/zjaf138
Genetics & basic scienceAnimal studyIn window
2025
A new Col1a1 conditional knock-in mouse model to study osteogenesis imperfecta
J Bone Miner Res · doi 10.1093/jbmr/zjae189
Genetics & basic scienceAnimal studyVerify date
2025
PMC12560462
Genetics & basic scienceLab studyIn window
2025
Comprehensive review of osteogenesis imperfecta: current treatments and future innovations
Human Gene Therapy · PubMed 39932815
Reviews & overviewsReviewIn window
2025
PubMed 40266851
Reviews & overviewsReviewIn window
2025
Osteogenesis imperfecta (Images in Clinical Medicine)
New England Journal of Medicine
Reviews & overviewsClinical imageVerify date
We invite you to connect with us in our shared commitment to improving the lives of those affected by Osteogenesis Imperfecta. Whether you are a healthcare professional, patient, or supporter, your involvement is invaluable. Join us in fostering a strong, informed, and supportive community.